Ribocomputing devices” have been developed by a team at the Wyss Institute.They can now be used by synthetic biologists to sense and interpret multiple signals in cells and logically instruct their ribosomes to produce different proteins. Ribocomputing devices could also be freeze-dried on paper, leading to paper-based biological circuits, including diagnostics that can sense and integrate several disease-relevant signals in a clinical sample.
A living programmable biocomputing device based on RNA
